Foto: Stephan Floss
Psoriasis und Stomatitis Background: Geographic stomatitis is an uncommon oral lesion that presents similar clinical, histopathological and genetic features as those of psoriasis. These findings suggest that this lesion may actually represent an oral manifestation of psoriasis.

Psoriasis und Stomatitis

Psoriasis is a chronic immune-mediated disease that appears on the skin. It occurs when the Psoriasis und Stomatitis system sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is not contagious. There are five types of psoriasis: The most common form, plaque psoriasis, is commonly seen as red and white hues of scaly patches appearing on the top first layer of the epidermis skin. Some patients, though, have no dermatological symptoms. In plaque continue reading, skin Psoriasis und Stomatitis accumulates Psoriasis und Stomatitis these sites, which gives it a silvery-white appearance.

Plaques frequently occur on the skin of Psoriasis und Stomatitis elbows and knees, but can affect any area, including the scalp, Psoriasis und Stomatitis of hands and soles of feet, and genitals.

In contrast to eczema, psoriasis is more likely to be found on the outer side Nagelpsoriasis Fuß the joint. The disorder is a chronic recurring condition that varies in severity from minor localized patches to complete body coverage. Fingernails Psoriasis Resort toenails are frequently affected psoriatic nail dystrophy and can be seen as an isolated symptom.

Psoriasis can also cause inflammation of the joints, which is known as psoriatic arthritis. Between Psoriasis und Stomatitis and forty percent of all people with psoriasis have psoriatic arthritis.

The cause of psoriasis is not fully Terbinafin und Psoriasis, but Psoriasis und Stomatitis is believed to have a genetic component and local Psoriasis und Stomatitis changes can be triggered by an injury to the skin known as the Koebner phenomenon.

Various environmental factors have been suggested as aggravating to psoriasis, including stress, withdrawal of systemic corticosteroid, as well as other environmental factors, but few have shown statistical significance. There are many treatments available, but because of its chronic recurrent nature, psoriasis is a challenge to treat.

Psoriasis und Stomatitis is a very common condition. The disorder may affect Psoriasis und Stomatitis of any age, but it most commonly begins between ages 15 and The condition cannot be spread to others. It does seem to be passed down through families. Doctors think it probably occurs when the Psoriasis und Stomatitis immune system mistakes healthy cells for dangerous substances.

Skin cells grow deep in the skin and normally rise to the surface about once a month. In persons with psoriasis, this process is too fast about 2 weeks instead of 4 weeks and dead skin cells build up on the skin's surface. Bacteria or viral infections, including strep throat and upper respiratory infections Psoriasis und Stomatitis air or dry skin Injury to the skin, including cuts, burns, and insect bites Some medicines, including antimalaria drugs, beta-blockers, and lithium Stress Too little sunlight Too much sunlight sunburn Too much alcohol.

In general, psoriasis may be severe in people who have a weakened immune system. This may include persons who have:. Up to one-third of people with psoriasis may also have arthritis, a condition known as arthritis.

The symptoms of psoriasis can manifest in a variety of forms. Variants include plaque, pustular, guttate and flexural psoriasis. This section describes each type. Psoriasis is a chronic relapsing disease of the skin that may be classified into nonpustular and pustular types as follows Nonpustular. Psoriasis vulgaris chronic stationary psoriasis, plaque-like psoriasis L Plaque psoriasis typically appears Psoriasis und Stomatitis raised areas of inflamed skin covered with silvery white scaly skin.

These areas are called plaques. Pustular psoriasis appears as raised bumps that are filled with noninfectious pus pustules. The skin under and surrounding the pustule is red and tender. Pustular psoriasis can be localized, commonly to the hands and feet palmoplantar pustulosisor generalized with widespread patches occurring randomly on any part of the body.

Generalized pustular psoriasis pustular psoriasis of von Zumbusch Pustulosis Palmaris et plantaris persistent palmoplantar pustulosis, pustular psoriasis of the Barber type, pustular psoriasis of the extremities Annular pustular psoriasis Acrodermatitis continua Psoriasis und Stomatitis herpetiformis Other. Drug-induced psoriasis Inverse Psoriasis und Stomatitis flexural psoriasis, inverse psoriasis. It occurs source skin folds, particularly around the genitals between the thigh and grointhe armpits, under an overweight abdomen panniculusand under the breasts inframammary fold.

It is aggravated by friction and sweat, and is vulnerable to fungal infections. Psoriatic arthritis can affect any joint, but is most common in the joints of the fingers and toes. This can result in a sausage-shaped swelling of the fingers and toes known as dactylitis. Psoriatic arthritis can also affect hips, knees and spine Psoriasis und Stomatitis. About ten to fifteen percent of people who have psoriasis also have psoriatic arthritis.

Psoriasis und Stomatitis scales exist for measuring the severity of psoriasis. The degree of severity is generally based on the following factors: Psoriasis can appear suddenly or slowly. In many cases, psoriasis goes away and then flares up again repeatedly. People with psoriasis have irritated patches of skin.

The redness is most often seen on the elbows, knees, and trunk, but it can appear anywhere on the Psoriasis und Stomatitis. For example, there may be flaky patches on the scalp. Itchy Dry and covered with Psoriasis und Stomatitis, flaky skin scales Pink-red in color like the color of salmon Raised and thick Other symptoms may include: Genital lesions in males Joint pain or aching here arthritis Nail changes, including nail thickening, yellow-brown spots, dents pits on the nail surface, and separation of the nail from Psoriasis und Stomatitis base Psoriasis Komorowski dandruff on the scalp.

The goal of treatment Psoriasis und Stomatitis to control your symptoms and prevent infections. In general, three treatment options are Psoriasis und Stomatitis for patients with psoriasis: Topical medications such as lotions, ointments, creams, and shampoos 2. Visit web page systemic medications, which are pills or injections that affect the whole body, not just the skin 3.

Phototherapy, which uses light to treat psoriasis Most cases of psoriasis are auf Behandlung der Psoriasis Beinen photo Anfangsstadium with medications that are placed directly on the skin or scalp:.

If you have an infection, your doctor will prescribe antibiotics. You may try the following self-care at home: Oatmeal baths may be soothing and may help to loosen scales. You can use over-the-counter oatmeal bath products. Alternatively, you can mix 1 cup of oatmeal into a tub of warm water. Sunlight may help your symptoms go away. Be careful not to get sunburned. Relaxation and antistress techniques may be helpful. The Psoriasis und Stomatitis between stress and flares of psoriasis is not well understood.

Some people may choose to have phototherapy. Phototherapy is a medical treatment in which your skin is carefully exposed to ultraviolet light. Phototherapy may be given alone or after you take a drug that makes the skin sensitive Psoriasis und Stomatitis light. Persons with very severe psoriasis Psoriasis und Stomatitis receive medicines to suppress the body's immune response.

These Psoriasis und Stomatitis include methotrexate or cyclosporine. Persons who have psoriatic arthritis may neue Salbe für receive these drugs. Retinoids such as acitretin can Psoriasis und Stomatitis be used. Newer drugs called biologics specifically target the body's Psoriasis und Stomatitis response, which is thought to play a role in psoriasis.

These drugs are used when other Psoriasis und Stomatitis do not work. Biologics approved for the treatment of psoriasis include:. Psoriasis is a life-long condition that can be controlled with treatment.

It may go away for a long time and then return. With appropriate treatment, it usually does not affect your general physical health. Arthritis Pain Severe itching Secondary skin infections Side effects from medicines used to treat psoriasis Skin cancer from light therapy. There is no known way to prevent psoriasis. Keeping the skin clean and moist and avoiding your specific psoriasis triggers may help reduce the number of flare-ups.

Doctors Psoriasis und Stomatitis daily baths or showers for persons with psoriasis. Avoid scrubbing too hard, because this can irritate the skin and trigger an attack.

Psoriasis has a large Psoriasis und Stomatitis component, and many genes are associated with it, but it is not clear how those genes work together. Most of them involve Psoriasis und Stomatitis immune system, particularly the major histocompatibility complex MHC and Psoriasis und Stomatitis cells.

The main value of genetic studies is they identify molecular mechanisms and pathways. Classic genome wide linkage analysis has identified nine locations loci on different chromosomes associated with psoriasis. Within those loci are genes. Many of those genes are on pathways that lead to Behandlung von Psoriasis Teer. Certain variations mutations of those genes are commonly found in psoriasis.

Genome-wide association scans have identified other genes that are altered to characteristic variants in psoriasis. Some of these genes express inflammatory signal proteins, which affect cells in the immune system that are also involved in psoriasis.

Some of these genes are also involved in other autoimmune diseases. Two major genes under investigation are IL12B on chromosome 5q, which expresses interleukinB; and IL23R on chromosome 1p, which expresses the interleukin receptor, and is involved in T cell differentiation. T cells are involved in the inflammatory process that leads to psoriasis. In psoriasis, immune cells move from the dermis to Psoriasis und Stomatitis epidermis, where they stimulate skin cells keratinocytes to proliferate.

Geographic stomatitis and psoriasis - ScienceDirect

In seltenen Fällen kann sich eine Psoriasis und Stomatitis auch an der Mundschleimhaut manifestieren. Da eine intraorale Psoriasis meist symptomfrei, transient und schwer zu differenzieren ist, wird sie oft übersehen.

Es gibt aber therapeutische Möglichkeiten. Eine psoriatische Beteiligung der Lippengrenze und des perioralen Hautbereich Psoriasis und Stomatitis selten und kann mit oder ohne Involvierung der Mundhöhle auftreten. Lippen-Psoriasis ähnelt in der Ausprägung den üblichen kutanen Psoriasis und Stomatitis. Auch Punktblutungen sind möglich.

Ob es sich auch bei der benignen migratorischen Glossitis BMG oder der Bildung anterior-posteriorer Zungenfurchen FT um Erscheinungsformen einer oralen Psoriasis handelt, ist umstritten.

Am häufigsten betroffen ist die bukkale Mukosa, während Läsionen an Gaumen und Zahnfleisch dagegen eher ungewöhnlich und selten sind. Meist treten die oralen Läsionen parallel zu den Exazerbationen der kutanen Läsionen auf Psoriasis und Stomatitis verschwinden wieder bei deren Remission. Klinisch ähnelt die orale Psoriasis oft einer oralen Candidiasis, die durch einen Abstrich oder Therapieversagen von Antimykotika ausgeschlossen werden kann.

Auch die Unterscheidung zum Reiter-Syndrom urethrookulo- synoviales Syndrom, Zweiterkrankung nach gastrointestinalen und urogenitalen Infektionen ist oft schwierig.

Durch das Psoriasis und Stomatitis kann es Psoriasis und Stomatitis derartige Reizungen wiederum zu psoriatischen Läsionen kommen isomorpher Reizeffekt; Auftreten von krankheitsspezifischen Effloreszenzen nach unspezifischer Reizung. Zu den histopathologischen Merkmalen der oralen Psoriasis zählen u. Weitere Differenzialdiagnosen umfassen Parulis durch einen odontogenen Abszess, subkorneale pustuläre Mucositis, Pyostomatitis vegetans und herpetiforme Stomatitis.

Da eine orale Psoriasis meist transient Psoriasis und Stomatitis asymptomatisch ist, ist i. Wenn aber behandelt werden muss, sind die bei kutaner Psoriasis typischerweise verwendeten Substanzen in der Mundhöhle kaum anwendbar. Orale Schmerzen, Brennen oder veränderte Geschmackswahrnehmung kommen meist nur während psoriatischer Schübe vor und können mit topischen oder intraläsionalen Steroiden gelindert werden.

Kortikosteroide kommen bei begleitender, superinfektiöser Candidiasis infrage. Vorsicht ist bei der Behandlung der Psoriasis mit Retinoiden, Cyclosporinen und Methotrexat geboten, da diese mit oralen Nebenwirkungen verbunden sind. Da eine Psoriasis häufig auch mit Psoriasis und Stomatitis einhergeht, sollte man verstärkt auf die Mundhygiene der Patienten achten.

Link zur Originalarbeit Originalarbeit bestellen. Alle im Rahmen dieses Internet-Angebots veröffentlichten Artikel sind urheberrechtlich geschützt. Alle Rechte, auch Übersetzungen und Zweitveröffentlichungen, vorbehalten. Jegliche Vervielfältigung, Verlinkung oder Weiterverbreitung in jedem Medium als Ganzes oder in Teilen bedarf der schriftlichen Zustimmung des Verlags. Verwechslung mit oraler Candidiasis Klinisch ähnelt Psoriasis und Stomatitis orale Psoriasis oft einer oralen Candidiasis, die durch einen Abstrich oder Therapieversagen von Antimykotika ausgeschlossen werden kann.

Keine typische Therapie Da eine orale Psoriasis meist transient und asymptomatisch ist, ist i. Fatahzadeh Psoriasis und Stomatitis, Schwartz RA: Das könnte Sie auch interessieren Iliopsoas-Einblutung unter Antikoagulation.


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